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Brand name: prograf
Generic name: Tacrolimus, Advagraf, Protopic
prograf description:
Patients with impaired renal function should be monitored closely as the dosage of Prograf may need to be reduced. Prograf (tacrolimus) drug InteractionsThere are 653 drug interactions with Prograf (tacrolimus)See also. Only physicians experienced in immunosuppressive therapy and management of organ transplant patients should prescribe Prograf. Prograf injection is contraindicated in patients with a hypersensitivity to HCO-60 (polyoxyl 60 hydrogenated castor oil). Hyperglycemia defined as two fasting plasma glucose levels ≥126 mg/dL was reported with the use of Prograf plus mycophenolate mofetil or azathioprine in 32% and 35% of heart transplant recipients in the US and European randomized studies, respectively, and may require treatment (see ADVERSE REACTIONS). In a randomized, open-label, multi-center trial (Study 1), 1589 kidney transplant patients received Prograf (Group C, n=401), sirolimus (Group D, n=399), or one of two cyclosporine regimens (Group A, n=390 and Group B, n=399) in combination with MMF and corticosteroids; all patients, except those in one of the two cyclosporine groups, also received induction with daclizumab.
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